Additionally, although we think that could be useful extract quantitative data from both MRI and MDCT images about the deep of the infiltration and the grade of a possible erosion of the mandible, a quantitative image analysis was not performed. Finally, whereas in our study the image analysis was conducted in consensus by two radiologist

during one reading session the reproducibily of the study must be verified by further studies which include this website different indipendent reading sessions. Conclusions In conclusion, the current study suggest that MRI could offer additional value in the evaluation of the relationship between the tumour and the mandible having higher sensitivity and negative predictive value although we reported none statistically significant differences and a similar diagnostic accuracy between GSK2118436 datasheet MRI and MDCT; we believe that further investigations with high resolution MRI and larger study population should be performed because of the importance of the correct SCC staging at imaging for either surgical or treatment management. Acknowledgements We are grateful to Maurizio Abrugia and Fabio Portieri for their technical assistance in performing MDCT and MRI examinations. References 1. Strong EW, Spiro RH: Cancer of the oral

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