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“Background: Total ankle arthroplasty has evolved over the past decade, and newer three-component implants have demonstrated favorable clinical results and improved survivorship. The present study analyzed the clinical and radiographic results of the first 240 total ankle arthroplasties performed by the authors with one of these new three-component prostheses.
Methods: Two hundred and forty consecutive primary total ankle arthroplasties were performed in 233 patients (115 women and 118 men; mean age, 61.6 years) between November 2003 and October
2007 with the Mobility prosthesis. Intraoperative and postoperative complications, reoperations, and failures were recorded. The American Orthopaedic Foot & Ankle Society hindfoot score and a visual analog scale score assessment of pain were determined at each follow-up visit. Range of ankle motion was measured on functional radiographs, and the radiographs click here were studied to assess component positioning, radiolucencies, new bone formation, and periprosthetic bone cysts.
Results: Two hundred and thirty-three of the arthroplasties were available for follow-up at least one year after surgery. The mean duration of follow-up was 32.8 +/- 15.3 months. There were ten intraoperative complications (4.2%) and twenty postoperative complications PHA-848125 molecular weight (8.6%). A reoperation
was necessary in eighteen ankles (7.7%). Five arthroplasties (2.1%) failed at a mean of twenty-seven months after surgery. The mean American Orthopaedic
Foot & Ankle Society hindfoot score improved from 48.2 to 84.1 points (p < 0.001). The mean pain level decreased from 7.7 to 1.7 points (p < 0.001). The mean total range of ankle motion improved from 19.8 degrees to 21.9 degrees (p < 0.001). The tibial component had a mean of 2.1 degrees of varus and a mean posterior slope of 6.0 degrees relative to the tibial axis. The prevalence of nonprogressive radiolucency Bucladesine clinical trial ranged from 1.8% to 37.3% in the ten zones surrounding the tibial component, and from 0 to 2.2% in the three zones surrounding the talar component.
Conclusions: The short-term clinical and radiographic results after Mobility total ankle arthroplasty are encouraging and are at least comparable with those associated with other modern three-component implants. The minimum duration of follow-up of one year is short, and studies with longer follow-up are needed to confirm our findings.”
“Purpose of reviewThis article reviews recent developments in the selection of the lung donor that aim to increase donor organ use. The scarcity of suitable donor organs continues to limit lung transplantation resulting in long waiting times and significant mortality for those patients awaiting transplantation.Recent findingsStrategies to expand the donor pool can substantially lift donor lung utilization rates from historically low levels of less than 15% to rates greater than 50% without inordinate risk of short-term or long-term complications.