For antioxidant activity, the most active alkaloid was asimilobine with ORAC value of 2.09 relative trolox equivalents. For antimicrobial activity, MK-2206 order some alkaloids showed significant minimal inhibitory concentration (MIC) values in the range of 25-100 mu gmL(-1). The most active compounds were the aporphinoids liriodenine, anonaine and asimilobine, some of them more active than the positive control.”
“Four compounds obtained from the ethyl acetate-soluble neutral fraction of methanol extracts of the Welsh onion (Allium
fistulosum L.) were purified by column chromatography using silica gel, octadecyl silane (ODS), and Sephadex LH-20 with a guided DPPH radical scavenging assay. After purification, the compounds were isolated by ODS-HPLC. The isolated compounds were identified as N-trans-feruloyl-3′-methoxytyramine (1), N-cis-feruloyl-3′-methoxytyramine find more (2), N-trans-p-coumaroyltyramine (3), and 3,5,7-trihydroxyflavone (kaempferol, 4) based on the spectroscopic
data of NMR and MS. To the best of our knowledge, this is the first study to identify compound 1-3 in the Welsh onion. Compound 1 and 2 showed significantly (p < 0.05) higher DPPH radical scavenging activities than compound 3.”
“We report the temperature dependence of photoluminescence (PL) spectra for InN. For a free-carrier concentration n=5.9×10(17) cm(-3) and low temperature, the main PL band is observed at 0.669 eV. The PL shift and broadening are described from 20 to 300 K based on electron-phonon interactions. Two discrete phonon sidebands (PSBs) are observed with corresponding phonon energy of similar to 69 meV. The PSB temperature shift and linewidth broadening are well described by previous theory.”
“Artemisia copa Phil. (Compositae) is used in popular medicine as a digestive and for gastric pains. The effects of A. copa aqueous extract and its isolated compounds were evaluated on isolated rat jejunum. The extract inhibited non-competitively the cumulative concentration-response curves induced by acetylcholine
and CaCl2. The tonic jejunum contractions induced by 80mM KCl were inhibited by A. copa. Relaxant effects of A. copa on the tonic contraction BEZ235 induced by 25mM KCl, [EC50: 0.94mgmL(-1) (0.64-1.39)], was not inhibited by glibenclamide, TEA, l-NAME or methylene blue. Chrysoeriol, spinacetin and luteolin (30 mu gmL(-1)), produced an antagonism on the CaCl2 concentration-response curve, showing an inhibition of the maximum contractions (70.0%+/- 5.0%, 49.1%+/- 4.5% and 77.0%+/- 3.5% of E-max, respectively), whereas tricin did not inhibit when the same concentration was used. A. copa exerts spasmolytic activity by blocking calcium channels and three isolated compounds could be, at least partly, responsible for the effect.”
“We report the dependence of the ferroelectric domain configuration and switching behavior on the shape (square versus round) of epitaxial BiFeO3 (BFO) nanostructures.