In dual task and passive viewing, this N1 latency-shift was abolished. Comparisons of “”low-attention”" (dual task or passive viewing) with “”high-attention”" conditions (single task or active viewing) revealed that attention only shortened N1 peak-latency
when the target was preceded by stimulus sequences with spatial and temporal regularity. P1 this website latency was unaffected by manipulation of top-down attention factors. Attentional factors are likely to modulate influences of spatiotemporal context through re-afferent projections at later stages of visual processing in regions of extrastriate cortex associated with the generators of the N1 waveform. (C) 2011 IBRO. Published by Elsevier Ltd. All rights reserved.”
“Objective: Repeat percutaneous endoluminal interventions for femoropopliteal occlusive disease are common, but the outcomes are poorly understood. We sought to determine the results of second-time femoropopliteal percutaneous transluminal angioplasty/stenting (SPTAS) and identify factors associated with success or failure of a continued
endoluminal revascularization strategy.
Methods: A retrospective review of patients undergoing multiple percutaneous endoluminal lower extremity interventions at a single institution 4-Hydroxytamoxifen mw from 2002 and 2009 identified 70 SPTAS in 70 limbs. Patient comorbidities, anatomic severity of disease, and procedural characteristics were analyzed with respect to outcomes with descriptive statistics, Kaplan-Meier curves, and Cox proportional hazards modeling. Patency rates were determined from the time of SPTAS.
Results: Patients included 37 men (63%) and 22 women (27%) at a mean age of 70 10 years. Indications for SPTAS included claudication in 54 limbs (77%) and critical limb ischemia (CLI) in 16 (23%). Median time from the initial endoluminal intervention to SPTAS was 330 days. Lesion Trans Atlantic Inter Society Consensus II (TASCII) classification was A in 18 (25.7%), B in 18 (25.7%), C in 25 (35.7%), and D in 9 (12.9%). Technical success was achieved in secondly 68 (97%) with low
rates of intraprocedural (10%) and postprocedural (4%) complications as well as initial clinical improvement in 61 (87%) patients. Over a median follow-up of 22.9 months following SPTAS, 2-year primary patency, secondary patency, limb salvage (in patients with CLI), and survival were 33% +/- 7%, 63% +/- 7%, 87% +/- 9%, and 88% +/- 5%, respectively. Cox proportional hazard modeling showed that SPTAS within 180 days of the initial endovascular intervention was the only significant predictor of failure of primary patency (hazard ratio, 2.65; 95% confidence interval, 1.4-5.2) and secondary patency (hazard ratio, 3.1; 95% confidence interval, 1.4-7.1) of SPTAS.
Conclusions: Second-time femoropopliteal angioplasty/stenting has excellent technical success but limited midterm primary and secondary patency.