Sample size was pre-calculated in order to ensure statistical pow

Sample size was pre-calculated in order to ensure statistical power (0.80) to be a minimum of 7 TH-302 research buy subjects Buparlisib per group. The statistical analysis was initially done by the Shapiro-Wilks normality test (W test) to verify if the sample showed normal distribution. Differences between groups were analyzed using Friedman test and Dunn post-test to compare age, upper muscle area, body composition, muscular strength and endurance, whist comparison for TBARS, TAS, CPK, uric acid, creatinine, and urea were performed using ANOVA with Tukey post-hoc test. Intra group (post x pre) analyzes were performed by paired t-Student test. In all calculations,

a critical level of p < 0.05 was fixed. GraphPad Prism® software was used for the analysis. Results Body composition There were no significant changes in weight, body fat, or lean body mass from baseline to post-supplementation values in the GC, GP or COT. Values for these parameters are displayed in Table 2. Table 2 Anthropometric

data before and after creatine supplementation and resistance training Group Height (cm) Weight (kg) CB-5083 research buy Body fat (%) Lean Body Mass (kg) Pre Post Pre Post Pre Post Pre Post GC 182 ± 6 182 ± 6 79 ± 10 80 ± 8 16.5 ± 6.2 16.2 ± 5.5 66 ± 5 67 ± 23 GP 181 ± 5.4 181 ± 5.4 80 ± 11 78 ± 9 12.3 ± 6.1 11.1 ± 5.9 69 ± 9 69 ± 9 COT 178 ± 6.9 178 ± 6.9 73 ± 13 75 ± 13 14.1 ± 7.7 13.8 ± 9.3 62 ± 6 64 ± 5 Values are expressed as mean ± SD; GC= creatine supplemented athletes; GP= placebo (malthodextrin) supplemented athletes; COT= non-supplemented control athletes. UMA and muscular tests There was no significant change in UMA from baseline to post measurement in the GC, GP or COT. However, there was significant increase in muscular strength (bench press) for GC (54 ± 9 kg and 63 ± 10 kg, respectively; p = 0.0356),

but not for GP (54 ± 19 kg and 58 ± 17 kg, respectively) or COT (48 ± 12 kg and 56 ± 11 kg, respectively). No significant differences in muscular endurance (bench press) were found, as seen in Table 3. Table 3 Muscular area (UMA), strength, and muscle endurance before and after creatine supplementation and resistance training Group UMA (cm2) Strength (kg) Muscle endurance (kg)   Pre Post Pre Post Pre Post GC 53 ± 9 58 ± 5 54 ± 9 63 ± eltoprazine 10 a 320 ± 215 368 ± 186 GP 56 ± 11 60 ± 12 54 ± 19 58 ± 17 311 ± 142 272 ± 83 COT 49 ± 8 52 ± 7 48 ± 12 56 ± 11 306 ± 148 279 ± 130 Values are expressed as mean ± SD; GC= creatine supplemented athletes; GP= placebo (malthodextrin) supplemented athletes; COT= non-supplemented control athletes. a P value = 0.0356 x Pre. Creatine phosphokinase (CPK), creatinine and urea There were no post-training differences among groups for CPK, creatinine or urea. Likewise, no differences were seen in each group when comparing pre- and post-supplementation values for CPK, creatinine, or urea. Table 4 presents CPK, creatinine and urea values.

Comments are closed.