Table 3 Characteristics of patients with impaired consciousness http://www.selleckchem.com/products/PLX-4032.html according to prehospital systolic blood pressure The proportions of patients with or without stroke

according to the SBP were noted in Table 4. Among patients with impaired consciousness, 31.0% had the proportion of stroke (SAH 1.5%, ICH 6.3%, and IS 23.2%, respectively). This significantly increased from 17.1% to 63.7% (P for trend <0.001). The trends by the subtype of stroke were qualitatively similar. Table 4 Proportion of stroke patients with impaired consciousness according to prehospital systolic blood pressure Figure 2 Inhibitors,research,lifescience,medical shows the relationship between SBP measured by EMS in prehospital settings and stroke occurrence among patients with impaired Inhibitors,research,lifescience,medical consciousness. The occurrence of stroke significantly increased with increasing SBP (AOR 1.34, 95% CI 1.33 to 1.35), and the AOR of the SBP>=200 mmHg group versus the SBP 101-120 mmHg group was 5.26 (95% CI 4.93 to 5.60). In the subgroup analyses in the Figure 3, the AOR for 20 mmHg-increment of SBP was 1.48 (95% CI 1.43 to 1.52) in SAH, 1.69 (95% Inhibitors,research,lifescience,medical CI 1.66 to 1.72) in ICH, and 1.14 (95% CI 1.13

to 1.15) in IS, and the AOR of SAH and ICH was greater than that of IS. The AOR of the SBP>=200 mmHg group versus the SBP 101-120 mmHg group was 9.76 (95% CI 7.86 to 12.12) Inhibitors,research,lifescience,medical in SAH, 16.16 (95% CI 14.43 to 18.10) in ICH, and 1.52 (1.42 to 1.62) in IS, and the AOR of SAH and ICH was greater than that of IS. Figure 2 Relationship between SBP measured by EMS personnel in prehospital settings

and the risk of stroke occurrence among patients with impaired consciousness. AORs: adjusted odds ratios. Figure 3 Relationships between SBP measured by EMS personnel in prehospital settings and the risk of stroke occurrence by its stroke Inhibitors,research,lifescience,medical subtype among patients with impaired consciousness. (A) SAH, (B) ICH, and (C) IS. AORs; adjusted odds ratios; SAH: subarachnoid … Table 5 shows the relationship between prehospital SBP and stroke Isotretinoin occurrence by impaired consciousness level. The AOR of the SBP>=200 mmHg group versus the SBP 101-120 mmHg group was 16.84 (95% CI 11.71 to 24.21) in mild disturbance and 11.55 (95% CI 6.70 to 19.90) in moderate disturbance among SAH patients, and 21.19 (95% CI 17.86 to 25.13) in mild disturbance, 13.58 (95% CI 10.71 to 17.22) in moderate disturbance, and 12.61 (95% CI 10.35 to 15.35) in severe disturbance among ICH patients. Table 5 Relationship between prehospital SBP and stroke occurrence by impaired consciousness level Discussion From this large registry of ambulance records, we demonstrated a significant positive relationship between prehospital SBP and the risk of stroke occurrence among emergency patients with impaired consciousness.