Three patients had simultaneous profunda femoral and superficial femoral artery injury. Fifty-nine out of the 113 (52%) patients who underwent operation {Selleck Anti-infection Compound Library|Selleck Antiinfection Compound Library|Selleck Anti-infection Compound Library|Selleck Antiinfection Compound Library|Selleckchem Anti-infection Compound Library|Selleckchem Antiinfection Compound Library|Selleckchem Anti-infection Compound Library|Selleckchem Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|buy Anti-infection Compound Library|Anti-infection Compound Library ic50|Anti-infection Compound Library price|Anti-infection Compound Library cost|Anti-infection Compound Library solubility dmso|Anti-infection Compound Library purchase|Anti-infection Compound Library manufacturer|Anti-infection Compound Library research buy|Anti-infection Compound Library order|Anti-infection Compound Library mouse|Anti-infection Compound Library chemical structure|Anti-infection Compound Library mw|Anti-infection Compound Library molecular weight|Anti-infection Compound Library datasheet|Anti-infection Compound Library supplier|Anti-infection Compound Library in vitro|Anti-infection Compound Library cell line|Anti-infection Compound Library concentration|Anti-infection Compound Library nmr|Anti-infection Compound Library in vivo|Anti-infection Compound Library clinical trial|Anti-infection Compound Library cell assay|Anti-infection Compound Library screening|Anti-infection Compound Library high throughput|buy Antiinfection Compound Library|Antiinfection Compound Library ic50|Antiinfection Compound Library price|Antiinfection Compound Library cost|Antiinfection Compound Library solubility dmso|Antiinfection Compound Library purchase|Antiinfection Compound Library manufacturer|Antiinfection Compound Library research buy|Antiinfection Compound Library order|Antiinfection Compound Library chemical structure|Antiinfection Compound Library datasheet|Antiinfection Compound Library supplier|Antiinfection Compound Library in vitro|Antiinfection Compound Library cell line|Antiinfection Compound Library concentration|Antiinfection Compound Library clinical trial|Antiinfection Compound Library cell assay|Antiinfection Compound Library screening|Antiinfection Compound Library high throughput|Anti-infection Compound high throughput screening| presented with additional trauma to other anatomical areas including bones / fracture dislocations and nerve lesions. Tables 3 and 4 illustrate the operative findings and the type of arterial repair done depending on the site of the injury. Table 3 Intraoperative findings in n = 113 patients with arterial vascular injuries Intrap. findings* Femoral Popliteal

Axillary Brachail Total   all pts: n = 34 all pts: n = 25 all pts: n = 10 all pts: n = 47 all pts: n = 113 Artery pts [n] pts [%] pts [n] pts [%] pts [n] pts [%] pts [n] pts [%] pts [n] pts [%] Thrombosed 3 9% 1 4% 3 30% 3 6% 10 9% Fully transsected 17 50% 19 76% Ferroptosis signaling pathway 5 50% 28 60% 69 61% incompletely transs. 11 32% 5 20% 4 40% 11 23% 31 27% Dissected 2 6% 0 0% 0 0% 4 9% 6 5% AV fistula 2 6% 0 0% 0 0% 1 2% 26 23% *Please note that multiple signs are possible. Pts = patients; AV fistula = traumatic arterio-venous fistula discovered. Table

4 Intraoperative vascular procedures done in n = 113 patients with arterial vascular injuries Vasc. Procedure Femoral Popliteal Axillary Brachial Total   all pts: n = 34 all pts: n = 25 all pts: n = 10 all pts: n = 47 all pts: n = 113   pts [n] pts [%] pts [n] pts [%] pts [n] pts [%] pts [n] pts [%] pts [n] pts [%] Lateral arteriorraphy 2 6% 0 0% 0 0% 1 2% 3 3% Primary end-to-end 3 9% 2 8% 2 20% 15 32% 22 19% Vein interpositiona 12 35% 17 68% 5 50% 28 60% 62 55% PTFE interposition 12 35% 0 0% 2 20 0 0% 114 12% Shunt/Stent 1 3% 1 4% 1 10% 2 4% 5 4%

Pts = patients; PTFE = Poly-tetra-fluoro-ethylen interposition graft. Sixteen of these 59 patients (27%) with additional injuries were hypotensive with a systolic BP < 90 mm Hg on admission. In contrast to them, only 10 patients of the 54 patients without concomitant injuries (19%) presented with systolic hypotension. Limb-saving surgery 113 patients were receiving an operation, and 92 (81%) of them had a successful primary reconstruction. This were all patients with axillary artery injury, 40 out of 46 (87%) patients with brachial artery injury, 24 out of 30 (80%) patients with femoral Oxymatrine and 18 out of 20 (90%) patients with popliteal artery injury. There were 12 (11%) patients who developed complications related to the initial interposition graft (bleeding, thrombosis); all of them were re-explored. All re-explorations were performed by the trauma surgeon in charge. Brachial artery results Of the 47 patients with brachial artery injury, one already presented with severe ischemia of the forearm and he underwent primary amputation for already overt muscle necrosis. Of the 46 patients who underwent brachial artery repair or graft, 6 (13%) patients had to be re-explored.